Reaction
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Timing
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Symptoms
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Allergic reaction (mild)
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- During the transfusion
- Up to 4 hours after the transfusion
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Hives or red welts on the skin, mild itching, rash, localized swelling, flushing (red face), wheezing, shortness of breath, or stridor (high-pitched noise or sound)
|
Anaphylactic reaction
|
- During the transfusion
- Up to 4 hours after the transfusion
|
Shortness of breath, Labored (working hard) breathing, Wheezing, Flushing (red face), Low blood pressure, Localized swelling, Chest tightness,Cramps |
Febrile nonhemolytic reaction
|
- During the transfusion
- Up to 4 hours after the transfusion
|
Fever (increase of 1° C or higher), chills, flushing (red face), nausea, headache, minor discomfort, or mild shortness of breath
|
Acute immune hemolytic reaction
|
|
Fever, red or brown urine, back pain, fast heart rate (tachycardia), abdominal pain, low blood pressure, feeling anxious, chills, chest pain, nausea, or fainting spells
|
Transfusion-related acute lung injury (TRALI)
|
|
Shortness of breath, trouble breathing, low blood pressure, fever, pulmonary edema
|
Transfusion-associated circulatory overload
|
|
Shortness of breath, fast heart rate (tachycardia), problems breathing when lying on back, abnormal blood pressure
|
Post-transfusion purpura (PUP)
|
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Purple spots on skin; nose bleed; bleeding from the urinary tract, abdomen, colon, or rectum; fever; or chills
|